Health blog

Diabetes: Types, Diagnosis, Complications, and Prevention

Posted on March 3, 2025

Diabetes

WHAT IS DIABETES MELLITUS?

Diabetes mellitus, or diabetes, is a condition where the body either produces insufficient insulin or becomes resistant to its effects. This results in increased glucose levels in the blood, a condition known as hyperglycemia.

WHAT IS INSULIN?

Insulin

Insulin is a peptide hormone created by the beta cells in the pancreas. Its primary function is to facilitate the entry of glucose into body cells, allowing it to be utilized for energy necessary for daily activities.

WHAT IS HYPERGLYCEMIA?

n individuals with diabetes, the body either produces too little insulin, none at all or is unresponsive to insulin's effects. This hampers glucose from entering cells, leading to its accumulation in the bloodstream and causing high blood sugar, or hyperglycemia.

WHAT IS PREDIABETES?

Pre-diabetes is a precursor stage to Type 2 diabetes mellitus (DM). In this condition, blood sugar levels are elevated beyond normal but not high enough to warrant a diagnosis of Type 2 DM.

TYPES OF DIABETES MELLITUS

The most common tyoes of diabetes mellitus includes:

  • Type 1 Dibetes Mellitus, formerly known as Insulin-dependent diabetes mellitus
  • Type 2 Diabetes Mellitus
  • Gestational Diabetes, Pregnancy induced diabetes.

TYPE 1 DIABETES MELLITUS

The exact cause of Type 1 diabetes is unknown, but it is believed to stem from an autoimmune disorder where the immune system mistakenly attacks and destroys the beta cells in the pancreas. This results in a significantly reduced capacity to produce insulin, necessitating external insulin administration. It primarily affects younger individuals, although adults can also develop it.

TYPE 2 DIABETES MELLITUS

Type 2 diabetes occurs when the body does not produce sufficient insulin and/or the cells become resistant to the insulin available. This type mainly affects adults, but it can also occur in children.

GESTATIONAL DIABETES MELLITUS (GDM)

Gestational diabetes mellitus develops during pregnancy. Women who experience GDM may not show any symptoms initially, making timely testing during the second trimester crucial..

Causes of GDM

The exact cause of Gestational Diabetes Mellitus (GDM) is unknown, but placental hormones can inhibit insulin action, leading to insulin resistance. This makes it difficult for the body to use insulin effectively, requiring increased production. Insufficient insulin can result in high blood glucose levels.

DIAGNOSIS OF DIABETES MELLITUS

Various blood tests are commonly used to diagnose diabetes, manage the condition, and evaluate treatment responses, these are:

  • Fasting Blood Sugar Levels (FBS):This blood test is typically conducted after the patient has fasted for at least 8-12 hours, meaning no food or drink (aside from water) for 8-10 hours before the test.
  • Random Blood Sugar Levels (RBS):This test can be performed at any time, regardless the patient has fasted or not
  • HbA1CThe HbA1C test provides an overview of a patient’s blood glucose levels over the past 2-3 months.
  • Oral Glucose Tolerance Test (OGTT)n this test, the patient consumes a glucose solution, and blood glucose levels are measured after 2 hours. It is often used to diagnose Gestational Diabetes Mellitus.

INTERPRETATION OF TESTS

Insulin

COMPLICATIONS OF DIABETES

SHORT TERM COMPLICATIONS

  • Hyperosmolar Hyperglycemic State (HHS)This condition is associated with very high blood glucose levels for very long periods with associated dehydration. It requires immediate medical treatment.
  • Diabetic Ketoacidosis (DKA)This condition is associated with the accumulation of ketones in the body as fat is utilized for energy instead of glucose. This is also a medical emergency.
  • HypoglycemiaThis condition is associated with severely low blood sugar levels that are below the healthy range.

LONG TERM COMPLICATIONS

Diabetes is associated with serious health complications. With the right treatment and lifestyle changes, one can prevent or delay the onset of these complications:

Long-term complications of diabetes mellitus are;

  • Cardiovascular complications
  • Chronic Kidney disease
  • Neuropathy (nerve damage)
  • DM-related eye disease
  • Foot complications
  • Oral complications
  • Hearing loss
  • Stroke
  • Skin complications
  • Depression

PREVENTION

Insulin

There is an autoimmune or genetic forms of diabetes mellitues i.e. Type 1 DM, but one can make lifestyle changes to prevent the risk of developing prediabetes, Type 2 DM and Gestational Diabetes. Some of the few measures one can take are:

  • Eating a healthy diet like the Mediterranean diet
  • Incorporating physical activity into daily routine
  • Work to achieve a healthy weight
  • Learn to manage stress
  • Limit alcohol intake
  • Maintain sleep hygiene
  • Quit smoking